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Egg Donation Program

 


Understanding the Egg Donation Program at Cape Fertility Clinic

Introduction

Egg donation represents a transformative option for many women facing fertility challenges. With a proven success rate and advanced techniques, Cape Fertility Clinic stands out as a leader in this field.

Our egg donation program has achieved an impressive 76.4% pregnancy rate based on 91 cycles performed in the third trimester of 2016, a figure that has remained consistent into the present. This article provides an in-depth look into the egg donation process at Cape Fertility Clinic, detailing everything from who can benefit from egg donation to the step-by-step procedures involved.

The Evolution of Egg Donation

Egg donation has a rich history, marked by significant milestones in reproductive medicine. The journey began with the first IVF pregnancy in 1978 in England, followed by Australia’s first egg donation pregnancy in 1984. South Africa joined the list of pioneering countries with its first successful egg donation pregnancy in 1986, which resulted in a twin birth. Today, egg donation is a standard procedure at Cape Fertility Clinic, on par with other advanced fertility treatments like IVF (in vitro fertilization) and ICSI (intracytoplasmic sperm injection).

Who Needs Egg Donation?

Egg donation is a viable solution for various fertility issues. Women who may benefit from this procedure include:

  1. Menopausal Women: As women reach menopause, their ovarian reserve diminishes, and their eggs are no longer viable for conception. Egg donation offers an opportunity to achieve pregnancy despite the natural decline in reproductive function.
  2. Women with Poor Ovarian Reserve: Some women experience a significant reduction in their number of eggs, often due to age or medical conditions. Egg donation can bypass this issue by using eggs from a young, healthy donor.
  3. Women with Repeated IVF Failures: For women who have undergone multiple unsuccessful IVF cycles, egg donation can provide a new avenue for achieving pregnancy by using eggs with a higher likelihood of successful fertilization.
  4. Women with Non-Responsive Ovaries: In cases where ovaries do not respond adequately to fertility medications, egg donation can be a solution.
  5. Women with Surgically Removed Ovaries or Those Who Have Undergone Chemotherapy: Surgical removal of ovaries or chemotherapy treatments can severely impact a woman’s ability to conceive. Egg donation offers a way to bypass these limitations.

The Process of Egg Donation

The egg donation process at Cape Fertility Clinic is meticulously designed to maximize success rates and ensure a smooth experience for all parties involved. Here is a step-by-step overview of the process:

  1. Selection of Donor: Donors are carefully selected from agencies that adhere to the SASREG (South African Society of Reproductive Medicine and Gynaecology) ethical guidelines. These agencies provide a list of potential donors, which can be obtained through your doctor or IVF coordinator. Cape Fertility Clinic works with these agencies to ensure the highest standards of care and ethics in donor selection.
  2. Donor and Recipient Synchronization: The donor’s menstrual cycle is synchronized with the recipient’s cycle to optimize the chances of successful implantation. This involves coordinating medication schedules and monitoring the cycles of both the donor and the recipient.
  3. Ovarian Stimulation and Egg Retrieval: The donor undergoes ovarian stimulation using fertility medications to produce multiple eggs. Once the eggs are mature, they are retrieved through a minor surgical procedure. This procedure is typically performed under sedation or anesthesia to ensure the donor’s comfort.
  4. Fertilization: Retrieved eggs are fertilized with sperm in the laboratory. This can be done through traditional IVF methods or ICSI, depending on the specific needs of the recipient.
  5. Embryo Transfer: Once fertilization is successful and embryos are developed, one or more embryos are selected for transfer into the recipient’s uterus. This procedure is generally straightforward and involves placing the embryo(s) into the uterus using a thin catheter.
  6. Pregnancy Testing and Follow-Up: After the embryo transfer, the recipient will undergo a pregnancy test to determine if implantation has been successful. Follow-up appointments are scheduled to monitor the progress of the pregnancy.

Finding an Egg Donor

At Cape Fertility Clinic, finding an egg donor is facilitated through reputable agencies that follow strict ethical guidelines. These agencies provide comprehensive profiles of potential donors, allowing recipients to make informed decisions. If you have not yet connected with an agency, you can request a list from our IVF coordinators by emailing Dawn Blank at dawn@capefertility.co.za.

Pre-Program Requirements

Before starting the egg donation program, recipients need to complete several steps:

  1. Medical Questionnaire: Recipients must fill out a detailed medical questionnaire and provide recent test results. This helps evaluate their suitability for the program and ensures that any underlying health issues are addressed.
  2. Required Tests for the Female Recipient:
    • Blood tests including FSH (Follicle-Stimulating Hormone) on day 3 of the cycle, HIV I and II, RPR (Syphilis), Hepatitis B Surface Antigen, Hepatitis C Antibody, Rubella IgG (immunity), TSH (Thyroid-Stimulating Hormone), and Prolactin.
    • Recent transvaginal pelvic ultrasound.
    • HSG (hysterosalpingogram), hysteroscopy, or saline infusion sonogram (may be requested by the treating doctor based on medical history and ultrasound results).
  3. Required Tests for the Male Partner:
    • Semen analysis.
    • Blood tests including HIV I and II, RPR (Syphilis), Hepatitis B Surface Antigen, and Hepatitis C Antibody.

Medication and Preparation

Before beginning the egg donation program, recipients need to obtain and administer specific medications. One of the key medications is Leuprolide acetate, a depot injection given on day 1 of the menstrual cycle. This medication suppresses natural ovulation to synchronize the recipient’s cycle with the donor’s.

Additional medications and treatments may be prescribed based on individual needs and the specific protocols of Cape Fertility Clinic.

The Role of Cape Fertility Clinic

Cape Fertility Clinic is committed to providing personalized and compassionate care throughout the egg donation process. Our experienced team of fertility specialists, embryologists, and support staff work collaboratively to ensure the best possible outcomes for our patients. We are dedicated to maintaining high standards of ethical practice and clinical excellence.

Conclusion

The egg donation program at Cape Fertility Clinic offers a beacon of hope for many women struggling with infertility. With our high success rates, state-of-the-art technology, and a compassionate approach, we provide a comprehensive solution for those seeking to build their families through egg donation. Our commitment to ethical practices and patient care ensures that each step of the process is handled with the utmost professionalism and respect. For more information or to start your journey with us, please contact our clinic and take the first step towards achieving your dream of parenthood.

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